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Small molecules are increasingly being used as tools to modulate signaling pathways and understand stem cell biology. As your research program advances into therapeutic applications, making the transition from research-grade to GMP-grade reagents is critical to the success of your project. Captivate Bio can facilitate this transition easier with the availability of both RUO and GMP-grade small molecules that are designed with enhanced quality testing and are suitable for use as ancillary reagents. GMP small molecules reduce the risk of unwanted genetic material, are easily scalable, and are manufactured following ICH Q7 guidelines.
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StemRegenin 1 or SR1 (GMP-grade) is an antagonist of the aryl hydrocarbon receptor (AHR). SR1 promotes the expansion human hematopoietic stem cells and the generation of progenitor cells. This product is GMP-grade and can be used in cell and gene therapy research applications. Bulk discounts and custom packaging available.
Thiazovivin (GMP-grade) is a novel ROCK inhibitor that promotes hESC survival after single-cell dissociation. Improves the efficiency of fibroblast reprogramming and induction of iPSCs. This small molecule is produced under GMP guidelines making it ideal for cell therapy research.
XAV939 (GMP-grade) is a potent tankyrase (TNKS) inhibitor. Promotes cardiomyocyte differentiation in mesoderm progenitor cells. Also used in neuronal differentiation protocols. Produced under GMP guidelines and is ideal for cell therapy research.
Y-27632 (GMP-grade) increases survival rate of hESCs and iPSCs undergoing cryopreservation. Used to reprogram fibroblasts to mature neurons and used as component of growth media for urothelial organoids. Produced under GMP guidelines and is ideal for cell therapy research.
Sourcing the right reagents or hard-to-find small molecules can be difficult and time-consuming. Captivate Bio can save you time by simplifying the sourcing of FBS, Human Platelet Lysate, classical media, small molecules, cytokines, and growth factors that meet your requirements, timeline, and budget. Let Captivate Bio be your first stop in providing access to thousands of research and GMP-grade reagents.
Contact us today to get started.
