Captivate Bio's ACY Cocktail Kit is a combination of three small molecules optimized to enhance cell proliferation, viability, and stemness in MSC stem cell cultures and organoid research.

BIRB796 is a highly potent inhibitor of p38 MAPK that enhances stem cell activity of cultured umbilical cord blood-derived hematopoietic cells. BIRB796 can be used in protocols for the chemical reprogramming of somatic cells to iPSCs.

CHIR99021 (GMP-grade) promotes self-renewal and pluripotency of embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). It can also maintain stem cells in an undifferentiated state and guide differentiation into specific lineages. Produced under GMP guidelines and is ideal for cell therapy research.

Cyclopamine is a Hedgehog (Hh) pathway antagonist with an IC50 of 46 nM in the Hh cell assay. Cyclopamine is also a selective Smo inhibitor.

EC23 (AGN 190205) is a stable synthetic retinoid analogue and induces neuronal differentiation.

IWP 2 is a potent inhibitor of Wnt processing and secretion (IC50 = 27nM). IWP-2 has also been used in protocols to reprogram somatic cells to chemically-induced PSCs.

IWP 4 is a potent inhibitor of Wnt/β-catenin signaling (IC50 = 25 nM). Has minimal effect on Notch and Hedgehog signaling pathways. Induces differentiation of cardiomyocytes from human ESCs and iPSCs.

Captivate Bio's MCDB 131 medium is commonly used in definitive endoderm differentiation of human pluripotent stem cells (hPSCs) as well as a basal medium for MSC differentiation.

Clinical grade PLTGold® Human Platelet Lysate is a xeno-free, heparin-free supplement for use in cGMP clinical applications. GMP products are further certified to be endotoxin free and is great for generating cells in large scale bioreactors. Master File available with the FDA available.

PLTGold contains all the growth factors and proteins that maximize cell growth without the need to worry about animal-based additives or lot-to-lot variability. This product is a research-grade, xeno-free, heparin-free supplement. US origin.