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EC23

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EC23 (AGN 190205) is a stable synthetic retinoid analogue and induces neuronal differentiation.

Grouped product items
SKUSIZEPRICE QTY
SML27A5 mg
$80.00
- +
SML27B10 mg
$150.00
- +
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Description
Specifications
More Information
SKUSML27
Molecular NameEC23
Size5 mg (SML27A), 10 mg (SML27B)
FormPowder
Alternative NamesAGN 190205; BASF-46928, EC 23
Chemical Name4- [2- (5,6,7,8- Tetrahydro- 5,5,8,8- tetramethyl- 2- naphthalenyl)ethynyl)- benzoic acid
Chemical FormulaC23H24O2
Molecular Weight332.44
CAS Number104561-41-3
Purity≥ 98.0% by LCMS
Physical AppearanceOff-white to light yellow
TargetRetinoid
Shelf-Life≥ 2 years (powder)
ShippingAMB
StorageStore at -20°C
Quality StatementThis product is For Research Use Only. Not for use in diagnostic or therapeutic procedures.

EC23 is a stable synthetic retinoid that displays similar activity to ATRA when tested on the embryonal carcinoma stem cell models. Also induces neural differentiation in human pluripotent embryonic stem cells and neuronal differentiation of human fetal neural progenitor cells (Christie, et al. 2008).

Alternative names: AGN 190205; BASF-46928, EC 23
Applications: Differentiation, Neuroscience, Stem Cell Biology
Cell types: Neural Cells, PSC-Derived, Neural Stem and Progenitor Cells, Neurons, Pluripotent Stem Cells

Resources
References & Publications
  • Maltman DJ, et al. Proteomic profiling of the stem cell response to retinoic acid and synthetic retinoid analogues: identification of major retinoid-inducible proteins. Mol Biosyst. 2009 May;5(5):458-71.
  • Christie VB, et al. Synthesis and evaluation of synthetic retinoid derivatives as inducers of stem cell differentiation. 2008. Org Biomol Chem 6: 3497
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