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An integrated stress response (ISR) inhibitor that promotes survival of pluripotent stem cells in culture when used in combination with Chroman 1 and Emricasan small molecules in the CEPT cocktail1.
Thiazovivin (GMP-grade) is a novel ROCK inhibitor that promotes hESC survival after single-cell dissociation. Improves the efficiency of fibroblast reprogramming and induction of iPSCs. This small molecule is produced under GMP guidelines making it ideal for cell therapy research.
Compound E is a γ-secretase and notch patchway inhibitor which induces neuronal differentiation. Compound E enhances growth inhibition, differentiation, and migration of neuroblastoma cells.
Highly potent and selective ROCK inhibitor with greater effectiveness at lower doses than Y27632. Enhances cell survival of dissociated hPSCs.
Thiazovivin is a novel ROCK inhibitor with IC50 of 0.5 μM in a cell-free assay, promotes hESC survival after single-cell dissociation. Improves the efficiency of fibroblast reprogramming and induction of iPSCs.
LDN193189 dihydrochloride is a potent and selective ALK2 and ALK3 inhibitor. LDN193189 is a potent inhibitor of the bone morphogenetic (BMP) pathway, shown to contribute to the differentiation of pluripotent stem cells into functional pancreatic beta cells.
Y-27632 is a cell-permeable, highly potent and selective inhibitor that Increases survival rates of hESc and iPSCs undergoing cryopreservation. Available in various pack sizes and in RUO and GMP-grade material.
Triiodothyronine Salt is an analog of thyroid hormone that selectively binds to and activates β1 thyroid hormone receptor (TRβ1). Regulates functions such as growth, metabolic activity, and hPSC differentiation. Stimulates respiratory activity at the mitochondrial level.
StemRegenin 1 or SR1 (GMP-grade) is an antagonist of the aryl hydrocarbon receptor (AHR). SR1 promotes the expansion human hematopoietic stem cells and the generation of progenitor cells. This product is GMP-grade and can be used in cell and gene therapy research applications. Bulk discounts and custom packaging available.
DAPT is a gamma γ-secretase inhibitor induces neuronal differentiation and promotes differentiation of pancreatic cells from hPSCs.