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Retinoic Acid is a metabolite of vitamin A that acts as a ligand for nuclear retinoic acid receptors. Retinoic acid has been used for the differentiation of embryonic stem cells into motor neurons and has also played an important role in protocols involving the differentiation of human pluripotent stem cells (PSCs) into functional pancreatic β cells.

SANT-1 is a potent antagonist of Smoothened (Smo), which in turn inhibits Hedgehog (Hh) signaling, specifically targeting Shh-LIGHT2 (IC50 of 20nM) and SmoA1-LIGHT2 (IC50 of 30nM). SANT-1 aids in the generation of functional human pancreatic beta cells from human pluripotent stem cells (PSCs).

DAPT is a gamma γ-secretase inhibitor induces neuronal differentiation and promotes differentiation of pancreatic cells from hPSCs.

EC23 (AGN 190205) is a stable synthetic retinoid analogue and induces neuronal differentiation.

Y-27632 (GMP-grade) increases survival rate of hESCs and iPSCs undergoing cryopreservation. Used to reprogram fibroblasts to mature neurons and used as component of growth media for urothelial organoids. Produced under GMP guidelines and is ideal for cell therapy research.

SB431542 (GMP-grade) is a potent small molecule inhibitor used for hESC neural differentiation and enhanced differentiation of PSCs into cardiomyocytes. Produced under GMP guidelines and is ideal for cell therapy research.

Retinoic Acid (GMP-grade) is used for the differentiation of embryonic stem cells into motor neurons and human pluripotent stem cells (PSCs) into functional pancreatic β cells. This small molecule is produced under cGMP guidelines and is ideal for cell therapy applications.

Y-27632 is a cell-permeable, highly potent and selective inhibitor that Increases survival rates of hESc and iPSCs undergoing cryopreservation. Available in various pack sizes and in RUO and GMP-grade material.

This RPMI 1640 Medium is formulated with L-glutamine, glucose, and with phenol red. This product is manufactured by Sartorius and available in case packs only.

DMEM/F12 basal media is typically used as a basal formulation in low-serum and serum-free media formulations, when culturing hPSCs and 3D organoids. This formulation is with HEPES and phenol red, and without L-glutamine. This product is manufactured by Sartorius and available in case packs only.