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An integrated stress response (ISR) inhibitor that promotes survival of pluripotent stem cells in culture when used in combination with Chroman 1 and Emricasan small molecules in the CEPT cocktail1.
Z-VAD-FMK is a cell-permeable, irreversible pan-caspase inhibitor. Inhibits caspase processing and apoptosis induction in tumor cells.
Captivate Bio's newly optimized CET Cocktail Kits are designed to enhance cell survival and promote growth of genetically stable hPSCs. Kits are configured to address specific workflows. Three versions include: CET Spark™ for 1L, CET Ignite™ for 5L, and CET Titan™ for 20L or more.
LDN193189 dihydrochloride is a potent and selective ALK2 and ALK3 inhibitor. LDN193189 is a potent inhibitor of the bone morphogenetic (BMP) pathway, shown to contribute to the differentiation of pluripotent stem cells into functional pancreatic beta cells.
Thiazovivin is a novel ROCK inhibitor with IC50 of 0.5 μM in a cell-free assay, promotes hESC survival after single-cell dissociation. Improves the efficiency of fibroblast reprogramming and induction of iPSCs.
Thiazovivin (GMP-grade) is a novel ROCK inhibitor that promotes hESC survival after single-cell dissociation. Improves the efficiency of fibroblast reprogramming and induction of iPSCs. This small molecule is produced under GMP guidelines making it ideal for cell therapy research.
New! Captivate Bio now offers PLUS™ Gamma Irradiated HPL in Cryobags. This product is manufactured and gamma irradiated under cGMP for use in clinical cell culture protocols and available in 250 ml bags.
DBZ is an inhibitor of γ-secretase aspartyl protease that improves efficiency of iPSC generation and production of iPSCs from mouse and human keratinocytes without KLF4 and CMYC.
Horse serum is often utilized in virus research, cell culture (e.g., cell differentiation, neural cell growth), IHC, and serology assay applications. Donor horse serum is a serum supplement collected from closely controlled donor herds.
Cyclopamine is a Hedgehog (Hh) pathway antagonist with an IC50 of 46 nM in the Hh cell assay. Cyclopamine is also a selective Smo inhibitor.
