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Retinoic Acid is a metabolite of vitamin A that acts as a ligand for nuclear retinoic acid receptors. Retinoic acid has been used for the differentiation of embryonic stem cells into motor neurons and has also played an important role in protocols involving the differentiation of human pluripotent stem cells (PSCs) into functional pancreatic β cells.
SANT-1 is a potent antagonist of Smoothened (Smo), which in turn inhibits Hedgehog (Hh) signaling, specifically targeting Shh-LIGHT2 (IC50 of 20nM) and SmoA1-LIGHT2 (IC50 of 30nM). SANT-1 aids in the generation of functional human pancreatic beta cells from human pluripotent stem cells (PSCs).
DAPT is a gamma γ-secretase inhibitor induces neuronal differentiation and promotes differentiation of pancreatic cells from hPSCs.
EC23 (AGN 190205) is a stable synthetic retinoid analogue and induces neuronal differentiation.
Y-27632 (GMP-grade) increases survival rate of hESCs and iPSCs undergoing cryopreservation. Used to reprogram fibroblasts to mature neurons and used as component of growth media for urothelial organoids. Produced under GMP guidelines and is ideal for cell therapy research.
SB431542 (GMP-grade) is a potent small molecule inhibitor used for hESC neural differentiation and enhanced differentiation of PSCs into cardiomyocytes. Produced under GMP guidelines and is ideal for cell therapy research.
Retinoic Acid (GMP-grade) is used for the differentiation of embryonic stem cells into motor neurons and human pluripotent stem cells (PSCs) into functional pancreatic β cells. This small molecule is produced under cGMP guidelines and is ideal for cell therapy applications.
Y-27632 is a cell-permeable, highly potent and selective inhibitor that Increases survival rates of hESc and iPSCs undergoing cryopreservation. Available in various pack sizes and in RUO and GMP-grade material.
A key supplement added to media to boost cell growth including hPSCs and human lymphocytes, also can be used with the CET Cocktail small molecule kit to enhance stem cell viability. Liquid, sterile-filtered.
SCF (Stem Cell Factor), Human, HEK293 is an essential factor in early hematopoiesis. Recombinant human protein expressed in human cell line for proper post-translational modifications and functionality.