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DMEM/F12 basal media is typically used as a basal formulation in low-serum and serum-free media formulations, when culturing hPSCs and 3D organoids. This formulation is with HEPES and phenol red, and without L-glutamine. This product is manufactured by Sartorius and available in case packs only.
Captivate Bio's DMEM, High Glucose is a widely used basal medium for supporting the growth of many different mammalian cells. This formulation contains 4 mM L-glutamine and 4500 mg/L glucose.
This RPMI 1640 Medium is formulated with no Phenol Red or L-glutamine. Captivate Bio's RPMI 1640 is suitable for the growth of a variety of mammalian cell lines.
Triiodothyronine Salt is an analog of thyroid hormone that selectively binds to and activates β1 thyroid hormone receptor (TRβ1). Regulates functions such as growth, metabolic activity, and hPSC differentiation. Stimulates respiratory activity at the mitochondrial level.
Retinoic Acid is a metabolite of vitamin A that acts as a ligand for nuclear retinoic acid receptors. Retinoic acid has been used for the differentiation of embryonic stem cells into motor neurons and has also played an important role in protocols involving the differentiation of human pluripotent stem cells (PSCs) into functional pancreatic β cells.
SANT-1 is a potent antagonist of Smoothened (Smo), which in turn inhibits Hedgehog (Hh) signaling, specifically targeting Shh-LIGHT2 (IC50 of 20nM) and SmoA1-LIGHT2 (IC50 of 30nM). SANT-1 aids in the generation of functional human pancreatic beta cells from human pluripotent stem cells (PSCs).
DAPT is a gamma γ-secretase inhibitor induces neuronal differentiation and promotes differentiation of pancreatic cells from hPSCs.
EC23 (AGN 190205) is a stable synthetic retinoid analogue and induces neuronal differentiation.
Y-27632 (GMP-grade) increases survival rate of hESCs and iPSCs undergoing cryopreservation. Used to reprogram fibroblasts to mature neurons and used as component of growth media for urothelial organoids. Produced under GMP guidelines and is ideal for cell therapy research.
SB431542 (GMP-grade) is a potent small molecule inhibitor used for hESC neural differentiation and enhanced differentiation of PSCs into cardiomyocytes. Produced under GMP guidelines and is ideal for cell therapy research.