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PLTMax® Human Platelet Lysate, clinical grade is for use in cGMP clinical applications and further certified to be endotoxin free. PLTMax is manufactured to meet the needs of research and development to ensure an easy transition to clinical manufacturing.
Compound E is a γ-secretase and notch patchway inhibitor which induces neuronal differentiation. Compound E enhances growth inhibition, differentiation, and migration of neuroblastoma cells.
Captivate Bio’s RESiVATE™ MSC Expansion Medium is a growth factor rich, xeno-free culture system that enables scientists the ability to customize culture conditions on the fly. Complete media with supplement contains growth factors to support rapid hMSC growth.
Triiodothyronine Salt is an analog of thyroid hormone that selectively binds to and activates β1 thyroid hormone receptor (TRβ1). Regulates functions such as growth, metabolic activity, and hPSC differentiation. Stimulates respiratory activity at the mitochondrial level.
Retinoic Acid is a metabolite of vitamin A that acts as a ligand for nuclear retinoic acid receptors. Retinoic acid has been used for the differentiation of embryonic stem cells into motor neurons and has also played an important role in protocols involving the differentiation of human pluripotent stem cells (PSCs) into functional pancreatic β cells.
SANT-1 is a potent antagonist of Smoothened (Smo), which in turn inhibits Hedgehog (Hh) signaling, specifically targeting Shh-LIGHT2 (IC50 of 20nM) and SmoA1-LIGHT2 (IC50 of 30nM). SANT-1 aids in the generation of functional human pancreatic beta cells from human pluripotent stem cells (PSCs).
DAPT is a gamma γ-secretase inhibitor induces neuronal differentiation and promotes differentiation of pancreatic cells from hPSCs.
EC23 (AGN 190205) is a stable synthetic retinoid analogue and induces neuronal differentiation.
Y-27632 (GMP-grade) increases survival rate of hESCs and iPSCs undergoing cryopreservation. Used to reprogram fibroblasts to mature neurons and used as component of growth media for urothelial organoids. Produced under GMP guidelines and is ideal for cell therapy research.
SB431542 (GMP-grade) is a potent small molecule inhibitor used for hESC neural differentiation and enhanced differentiation of PSCs into cardiomyocytes. Produced under GMP guidelines and is ideal for cell therapy research.