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Cyclopamine is a Hedgehog (Hh) pathway antagonist with an IC50 of 46 nM in the Hh cell assay. Cyclopamine is also a selective Smo inhibitor.
Horse serum is often utilized in virus research, cell culture (e.g., cell differentiation, neural cell growth), IHC, and serology assay applications. Donor horse serum is a serum supplement collected from closely controlled donor herds.
Forskolin is a cell-permeable diterpene that directly activates adenylyl cyclase, for the maintenance and reprogramming of stem cells.
Hedgehog pathway activator; Activates Smoothened (SMO). Purmorphamine has been shown to promote differentiation of motor neurons from human pluripotent stem cells and human and mouse mesenchymal stem cells.
Activin A, a multifunctional cytokine, is a member of TGF-β family. Activin A Protein, Human/Mouse/Rat (HEK293) is produced in HEK293 cells, and consists of 117 amino acids.
Captivate Bio's Soybean Trypsin Inhibitor (SBTI) is used in research primarily to inactivate trypsin during cell culture to stop the enzyme from degrading cells. This product is a powder format and available in various pack sizes including custom.
L-Glutamine Solution (200 mM) is a ready-to-use stock solution. L-glutamine is an essential amino acid that is a required additive to most cell culture media, facilitating the storage and transfer of nitrogen to the cells in culture.
M-CSF is a recombinant mouse pro-inflammatory cytokine involved in the development and proliferation of monocyte/macrophage cells. M-CSF is essential for many macrophage-related functions, and vital for differentiation of iPSCs into macrophages.
Captivate Bio's newly optimized CET Cocktail Kits are designed to enhance cell survival and promote growth of genetically stable hPSCs. Kits are configured to address specific workflows. Three versions include: CET Spark™ for 1L, CET Ignite™ for 5L, and CET Titan™ for 20L or more.
Kartogenin potently induces differentiation of human mesenchymal stem cells into chondrocytes (EC50 = 100 nM). Reduces disease severity in a mouse model of osteoarthritis; displays protective effects against osteoarthritic stimuli in mature chondrocytes in vitro.