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Activin A, Human/Mouse/Rat, HEK293

Activin A, a multifunctional cytokine, is a member of TGF-β family. Activin A Protein, Human/Mouse/Rat (HEK293) is produced in HEK293 cells, and consists of 117 amino acids.

Grouped product items
SKU	SIZE	PRICE	QTY
CYK06L	50 ug	$535.00	- +
CYK06F	100 ug	$775.00	- +

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Description

Specifications

More Information
SKU	CYK06-CT
Form	Lyophilized powder
Alternative Names	rHuActivin A; Inhibin beta A chain; INHBA; Activin A
Species	Human
Source/Origin	HEK293
Tag	Tag Free
Molecular Weight	Approximately 13-15 kDa
Endotoxin	< 0.01 EU/μg, determined by LAL method
Storage	Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Shipping	Room Temp

Activin A, a multifunctional cytokine, is a member of TGF-β family. Activin A first binds to the type II activin receptors (ActIIRA or ActRIIB) on the surface and then recruits and phosphorylates type I Activin receptors (ActRI). Activin A primarily signal through SMAD2/3 proteins to regulate a variety of functions, including inflammation, fibrosis, and tumorigenesis. Activin A Protein, Human/Mouse/Rat, HEK293 is produced in HEK293 cells, and consists of 117 amino acids.

Resources

References

Ge J, et al. Involvement of CHOP in activin A induced myeloma NS 1 cell apoptosis. Oncol Rep. 2019;42(6):2644-2654.
Enrrico Bloise, et al. Activin A in Mammalian Physiology. Physiol Rev. 2019 Jan 1;99(1):739-780.
N L Frigon Jr, et al. Regulation of globin gene expression in human K562 cells by recombinant activin A. Blood. 1992 Feb 1;79(3):765-72.
D D Wu, et al. Expression of the activin axis and neuronal rescue effects of recombinant activin A following hypoxic-ischemic brain injury in the infant rat. Brain Res. 1999 Jul 24;835(2):369-78.
B Attardi, et al. Rapid stimulatory effect of activin-A on messenger RNA encoding the follicle-stimulating hormone beta-subunit in rat pituitary cell cultures. Mol Endocrinol. 1990 May;4(5):721-6.

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