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Forskolin is a cell-permeable diterpene that directly activates adenylyl cyclase, for the maintenance and reprogramming of stem cells.
An integrated stress response (ISR) inhibitor that promotes survival of pluripotent stem cells in culture when used in combination with Chroman 1 and Emricasan small molecules in the CEPT cocktail1.
Thiazovivin is a novel ROCK inhibitor with IC50 of 0.5 μM in a cell-free assay, promotes hESC survival after single-cell dissociation. Improves the efficiency of fibroblast reprogramming and induction of iPSCs.
Thiazovivin (GMP-grade) is a novel ROCK inhibitor that promotes hESC survival after single-cell dissociation. Improves the efficiency of fibroblast reprogramming and induction of iPSCs. This small molecule is produced under GMP guidelines making it ideal for cell therapy research.
LDN193189 dihydrochloride is a potent and selective ALK2 and ALK3 inhibitor. LDN193189 is a potent inhibitor of the bone morphogenetic (BMP) pathway, shown to contribute to the differentiation of pluripotent stem cells into functional pancreatic beta cells.
New! Captivate Bio now offers PLUS™ Gamma Irradiated HPL in Cryobags. This product is manufactured and gamma irradiated under cGMP for use in clinical cell culture protocols and available in 250 ml bags.
DBZ is an inhibitor of γ-secretase aspartyl protease that improves efficiency of iPSC generation and production of iPSCs from mouse and human keratinocytes without KLF4 and CMYC.
Horse serum is often utilized in virus research, cell culture (e.g., cell differentiation, neural cell growth), IHC, and serology assay applications. Donor horse serum is a serum supplement collected from closely controlled donor herds.
Cyclopamine is a Hedgehog (Hh) pathway antagonist with an IC50 of 46 nM in the Hh cell assay. Cyclopamine is also a selective Smo inhibitor.
Captivate Bio's Soybean Trypsin Inhibitor (SBTI) is used in research primarily to inactivate trypsin during cell culture to stop the enzyme from degrading cells. This product is a powder format and available in various pack sizes including custom.