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LDN193189 (GMP-grade) is a potent inhibitor of the BMP pathway, shown to contribute to the differentiation of pluripotent stem cells into functional pancreatic beta cells. This small molecule is produced under GMP guidelines and is used in cell therapy applications.
Y-27632 (GMP-grade) increases survival rate of hESCs and iPSCs undergoing cryopreservation. Used to reprogram fibroblasts to mature neurons and used as component of growth media for urothelial organoids. Produced under GMP guidelines and is ideal for cell therapy research.
An integrated stress response (ISR) inhibitor that promotes survival of pluripotent stem cells in culture when used in combination with Chroman 1 and Emricasan small molecules in the CEPT cocktail1.
Thiazovivin (GMP-grade) is a novel ROCK inhibitor that promotes hESC survival after single-cell dissociation. Improves the efficiency of fibroblast reprogramming and induction of iPSCs. This small molecule is produced under GMP guidelines making it ideal for cell therapy research.
Highly potent and selective ROCK inhibitor with greater effectiveness at lower doses than Y27632. Enhances cell survival of dissociated hPSCs.