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Compound E is a γ-secretase and notch patchway inhibitor which induces neuronal differentiation. Compound E enhances growth inhibition, differentiation, and migration of neuroblastoma cells.
Captivate Bio's RPMI 1640 Medium is suitable for a variety of mammalian cells. This formulation is modified without L-glutamine or glucose and with Phenol Red.
100% Cotton, Gender Neutral, Midnight Black Tee, Printed in USA. For each shirt sold, proceeds will be donated to local STEM programs.
Triiodothyronine Salt is an analog of thyroid hormone that selectively binds to and activates β1 thyroid hormone receptor (TRβ1). Regulates functions such as growth, metabolic activity, and hPSC differentiation. Stimulates respiratory activity at the mitochondrial level.
Retinoic Acid is a metabolite of vitamin A that acts as a ligand for nuclear retinoic acid receptors. Retinoic acid has been used for the differentiation of embryonic stem cells into motor neurons and has also played an important role in protocols involving the differentiation of human pluripotent stem cells (PSCs) into functional pancreatic β cells.
SANT-1 is a potent antagonist of Smoothened (Smo), which in turn inhibits Hedgehog (Hh) signaling, specifically targeting Shh-LIGHT2 (IC50 of 20nM) and SmoA1-LIGHT2 (IC50 of 30nM). SANT-1 aids in the generation of functional human pancreatic beta cells from human pluripotent stem cells (PSCs).
DAPT is a gamma γ-secretase inhibitor induces neuronal differentiation and promotes differentiation of pancreatic cells from hPSCs.
Captivate Bio's CET Cocktail Kit is comprised of the small molecules used in the CEPT strategy: Chroman 1, Emricasan, and Trans-IRIB (CET). These small molecules have been found to enhance cell survival and promote clonal growth of genetically stable hPSCs.
EC23 (AGN 190205) is a stable synthetic retinoid analogue and induces neuronal differentiation.
Y-27632 (GMP-grade) increases survival rate of hESCs and iPSCs undergoing cryopreservation. Used to reprogram fibroblasts to mature neurons and used as component of growth media for urothelial organoids. Produced under GMP guidelines and is ideal for cell therapy research.
