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EC23 (AGN 190205) is a stable synthetic retinoid analogue and induces neuronal differentiation.
Captivate Bio's MCDB 131 medium is commonly used in definitive endoderm differentiation of human pluripotent stem cells (hPSCs) as well as a basal medium for MSC differentiation.
Medium 199 is widely used in virology and vaccine production. This formulation is modified with Earle's salts and without L-glutamine or HEPES.
Kartogenin potently induces differentiation of human mesenchymal stem cells into chondrocytes (EC50 = 100 nM). Reduces disease severity in a mouse model of osteoarthritis; displays protective effects against osteoarthritic stimuli in mature chondrocytes in vitro.
Compound E is a γ-secretase and notch patchway inhibitor which induces neuronal differentiation. Compound E enhances growth inhibition, differentiation, and migration of neuroblastoma cells.
RepSox is a potent and selective transforming growth factor-beta receptor I/activin like kinase 5 (TGF-β-RI/ALK5) inhibitor. RepSox was found to replace the function of Sox2 to induce reprogramming of iPS cells.
Emricasan is an irreversible pan-caspase inhibitor. A key small molecule component of the published CEPT cocktail, enhances cell survival, clonogenicity, and cytoprotection of hPSCs.
A83-01 has been extensively used in various studies to modulate TGF-β signaling pathways, impacting cellular differentiation, organoid growth, and disease modeling. A83-01 is supplied as a lyophilized powder.
Waymouth's Media is used for the establishment of carcinoma cell lines from pleural effusions and the growth of potentially tumorigenic cells. This product is manufactured by Sartorius and available in case packs only.
Modified MCDB 153 medium is specific for human epidermal keratinocyte culture, clonal growth of chicken embryo fibroblasts or Chinese Hamster Ovary (CHO) cells using low levels of Fetal Bovine Serum. This product is made-to-order by Sartorius and available in case packs only.
