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Captivate Bio's endotoxin-free DPBS (no calcium, no magnesium) is a premium, high quality salt solution for the life science and therapeutic research markets. This product includes enhanced quality control with mycoplasma and endotoxin testing (<0.005 EU/ml).
Potent and selective GSK3 inhibitor (Ki= 9 nM for GSK-3α). Has little activity against 24 other protein kinases (IC50 > 10 μM). Stimulates glycogen synthesis, gene transcription and is cardio- and neuroprotective.
IWP 2 is a potent inhibitor of Wnt processing and secretion (IC50 = 27nM). IWP-2 has also been used in protocols to reprogram somatic cells to chemically-induced PSCs.
Captivate Bio's MEM Non-Essential Amino Acids (MEM-NEAA) is one of the most commonly used cell culture supplements added to cell culture media which stimulates cell growth and viability.
A83-01 has been extensively used in various studies to modulate TGF-β signaling pathways, impacting cellular differentiation, organoid growth, and disease modeling. A83-01 is supplied as a lyophilized powder.
PD0325901 is a selective, non-ATP-competitive inhibitor of the mitogen-activated protein kinase (MAPK/ERK kinase, or MEK) that suppresses expression of p-ERK1/2 and induces apoptosis. PD0325901 enhances generation of induced pluripotent stem cells (iPSCs).
Captivate Bio's standard Fetal Bovine Serum (US Origin) offers excellent value at an extremely affordable price. Our standard FBS provides consistent and rapid cell growth for basic cell culture research, standard quality tests included. Bulk discounts of 25 bottles or more available.
IWP 4 is a potent inhibitor of Wnt/β-catenin signaling (IC50 = 25 nM). Has minimal effect on Notch and Hedgehog signaling pathways. Induces differentiation of cardiomyocytes from human ESCs and iPSCs.
Kartogenin potently induces differentiation of human mesenchymal stem cells into chondrocytes (EC50 = 100 nM). Reduces disease severity in a mouse model of osteoarthritis; displays protective effects against osteoarthritic stimuli in mature chondrocytes in vitro.
Captivate Bio's charcoal stripped fetal bovine serum is for researchers requiring decreased levels of various hormones in their studies. Sterile-filtered, mycoplasma-tested, and viral-screened.
