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LDN193189 dihydrochloride is a potent and selective ALK2 and ALK3 inhibitor. LDN193189 is a potent inhibitor of the bone morphogenetic (BMP) pathway, shown to contribute to the differentiation of pluripotent stem cells into functional pancreatic beta cells.
New! Captivate Bio now offers PLUS™ Gamma Irradiated HPL in Cryobags. This product is manufactured and gamma irradiated under cGMP for use in clinical cell culture protocols and available in 250 ml bags.
DBZ is an inhibitor of γ-secretase aspartyl protease that improves efficiency of iPSC generation and production of iPSCs from mouse and human keratinocytes without KLF4 and CMYC.
Horse serum is often utilized in virus research, cell culture (e.g., cell differentiation, neural cell growth), IHC, and serology assay applications. Donor horse serum is a serum supplement collected from closely controlled donor herds.
Cyclopamine is a Hedgehog (Hh) pathway antagonist with an IC50 of 46 nM in the Hh cell assay. Cyclopamine is also a selective Smo inhibitor.
Captivate Bio's Soybean Trypsin Inhibitor (SBTI) is used in research primarily to inactivate trypsin during cell culture to stop the enzyme from degrading cells. This product is a powder format and available in various pack sizes including custom.
L-Glutamine Solution (200 mM) is a ready-to-use stock solution. L-glutamine is an essential amino acid that is a required additive to most cell culture media, facilitating the storage and transfer of nitrogen to the cells in culture.
M-CSF is a recombinant mouse pro-inflammatory cytokine involved in the development and proliferation of monocyte/macrophage cells. M-CSF is essential for many macrophage-related functions, and vital for differentiation of iPSCs into macrophages.
Hedgehog pathway activator; Activates Smoothened (SMO). Purmorphamine has been shown to promote differentiation of motor neurons from human pluripotent stem cells and human and mouse mesenchymal stem cells.
Activin A, a multifunctional cytokine, is a member of TGF-β family. Activin A Protein, Human/Mouse/Rat (HEK293) is produced in HEK293 cells, and consists of 117 amino acids.