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StemRegenin 1 or SR1 is an antagonist of the aryl hydrocarbon receptor (AHR). SR1 promotes the expansion human hematopoietic stem cells and the generation of progenitor cells. This small molecule is available in custom pack sizes.
Purmorphamine (GMP-grade), a hedgehog pathway activator, has been shown to promote differentiation of motor neurons from human pluripotent stem cells and human and mesenchymal stem cells. This product is manufactured under cGMP and is ideal for cell therapy applications.
XAV939 (GMP-grade) is a potent tankyrase (TNKS) inhibitor. Promotes cardiomyocyte differentiation in mesoderm progenitor cells. Also used in neuronal differentiation protocols. Produced under GMP guidelines and is ideal for cell therapy research.
Forskolin is a cell-permeable diterpene that directly activates adenylyl cyclase, for the maintenance and reprogramming of stem cells.
PD0325901 (GMP-grade) is a potent, selective, and orally available inhibitor of MEK1/2, a protein crucial for the MAPK signaling pathway that regulates cell growth and proliferation. This small molecule is produced under cGMP and is ideal for cell therapy applications.
The NEST® BioFactory™ culture chambers are compact, multi-layer flasks designed for small scale, single-use research or commercial cell production. Systems are available in 2, 5, 10, and 40-layers with various wide and narrow mouth caps available.
Captivate Bio’s NEST Disposable Pasteur Pipets are lightweight, flexible and durable. These pipets are available in 1, 2, 3, 5 mL and 10 mL sizes, individually wrapped, and available in bulk case packs.
Captivate Bio’s CB-27 Supplement is a serum-free solution optimized for the growth and viability of neuronal cells and is used with the culture of a variety of cell types.
A83-01 has been extensively used in various studies to modulate TGF-β signaling pathways, impacting cellular differentiation, organoid growth, and disease modeling. A83-01 is supplied as a lyophilized powder.