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Purmorphamine (GMP-grade), a hedgehog pathway activator, has been shown to promote differentiation of motor neurons from human pluripotent stem cells and human and mesenchymal stem cells. This product is manufactured under cGMP and is ideal for cell therapy applications.
Captivate Bio offers a portfolio of GMP-grade small molecules. GMP-grade small molecules are produced under well establish, controlled cGMP guidelines and are used as ancillary reagents in the generation of stem cells and in reprogramming, self-and differentiation workflows for cell therapy applications.
Purmorphamine is a small molecule that activates the hedgehog signaling pathway by directly binding to and activating the Smoothened (Smo) receptor. It is used in stem cell research to promote osteogenesis (bone formation) and neural differentiation, and has also been studied for its neuroprotective effects.
As your research program advances into therapeutic applications, making the transition from research-grade to GMP-grade reagents is critical to the success of your project. Captivate Bio can facilitate this transition easier with the availability of both RUO and GMP-grade small molecules that are designed with enhanced quality testing and are suitable for use as ancillary reagents.
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PDF | Download our Small Molecules for Cell and Gene Therapy Research flyer. Now offering RUO and GMP-grade small molecules for a variety of cell types.
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