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Captivate Bio's MCDB 131 was originally developed by the researchers Knedler and Ham for the low-protein and serum free growth of human microvascular endothelial cells (HMVEC). Since its development, this medium has been used for this cell type and others such as liver, smooth muscle, cardiomyocytes. It is one of a group of MCDB media which were designed to provide a defined, serum, and optimally balanced nutritional environment for various mammalian cell types.
We offer MCDB 131 cell culture media off-the-shelf without L-glutamine and with or without Phenol Red. MCDB 131 is also available as a custom made-to-order media configured to fit your project and your budget. Our custom media services can provide you with the exact formulation you need, including custom components, concentration, packaging, and QC testing. All our cell culture media products are manufactured following cGMP guidelines and in ISO-certified facilities to ensure high quality product performance.
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Captivate Bio's MCDB 131 medium is commonly used in definitive endoderm differentiation of human pluripotent stem cells (hPSCs) as well as a basal medium for MSC differentiation.
Captivate Bio's MCDB 131 Medium contains many components not found in traditional basal media, such as trace elements, putrescine, adenine, thymidine, and higher levels of some amino acids and vitamins. This formulation is without L-glutamine and without Phenol Red making it ideal for cell therapy research.
