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Flt3-Ligand, Human, HEK293

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Engineered Flt3-Ligand human recombinant protein expressed in human HEK23 cells for proper post-translational modifications. Promotes differentiation and expansion of multiple hematopoietic cell lineages.

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SKUSIZEPRICE QTY
CYK01F100 ug
$625.00
- +
CYK01H1 mg
$3,850.00
- +
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Description
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SKUCYK01-CT
FormLyophilized powder.
SpeciesHuman
SourceHEK293
TagC-6*His
Alternative NamesFlt3L, FLT3-LG, FMS-like Tyrosine Kinase 3 Ligand
AccessionP49771 (T27-P184)
Gene ID2323 [NCBI]
Molecular Weight24-32 kDa
PurityGreater than 95% as determined by reducing SDS-PAGE.
Endotoxin<0.01 EU/μg, determined by LAL method.
ReconstitutionReconstitute at 100 µg/mL in ddH2O Store with carrier protein to improve stability.
Shelf-Life>2 years (lyophilized)
StorageStore at -20°C
ShippingRoom Temp
Quality StatementThis product is for Research Use Only and is not intended for therapeutic or diagnostic use.

Flt3-Ligand (FMS-related Receptor Tyrosine Kinase 3 Ligand) promotes the differentiation or expansion of multiple hematopoietic cell lineages including monocytes, immature dendritic cells, and early B cell lineage cells.  Flt3-Ligand works in combination with other cytokines to produce the following effects:

  • Promotes myeloid differentiation and mobilization of hematopoietic stem cells
  • Induces NK cell development
  • Induces terminal B cell maturation

Flt3-Ligand signals through the tyrosine kinase receptor Flt-3/Flk-2.

Applications: Hematopoietic stem cell expansion and differentiation

Cell types: Hematopoietic stem cells (HSC), NK cells, T cells

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