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SB431542 is a potent small molecule inhibitor of TGF-β signaling. Used for hESC neural differentiation and enhanced differentiation of PSCs into cardiomyocytes. Replaces SOX2 in reprogramming of fibroblasts into iPSCs.
UM171 is a highly potent small molecule for Hematopoietic stem cell (HSC) expansion and differentiation. Lyophilized powder in various sizes. This product is for research use only.
Potent and selective GSK3 inhibitor (Ki= 9 nM for GSK-3α). Has little activity against 24 other protein kinases (IC50 > 10 μM). Stimulates glycogen synthesis, gene transcription and is cardio- and neuroprotective.
SU5402 is a potent and selective inhibitor of VEGFR-2, FGFR-1, and PDGFRB.
IWP 4 is a potent inhibitor of Wnt/β-catenin signaling (IC50 = 25 nM). Has minimal effect on Notch and Hedgehog signaling pathways. Induces differentiation of cardiomyocytes from human ESCs and iPSCs.
A key supplement added to media to boost cell growth including hPSCs and human lymphocytes, also can be used with the CET Cocktail small molecule kit to enhance stem cell viability. Liquid, sterile-filtered.
Captivate Bio’s NEST Disposable Pasteur Pipets are lightweight, flexible and durable. These pipets are available in 1, 2, 3, 5 mL and 10 mL sizes, individually wrapped, and available in bulk case packs.
Activin A, a multifunctional cytokine, is a member of TGF-β family. Activin A Protein, Human/Mouse/Rat (HEK293) is produced in HEK293 cells, and consists of 117 amino acids.
A83-01 has been extensively used in various studies to modulate TGF-β signaling pathways, impacting cellular differentiation, organoid growth, and disease modeling. A83-01 is supplied as a lyophilized powder.
New! Captivate Bio now offers PLUS™ Gamma Irradiated HPL in Cryobags. This product is manufactured and gamma irradiated under cGMP for use in clinical cell culture protocols and available in 250 ml bags.
