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Captivate Bio's Exosome-Depleted FBS is designed to enhance the accuracy and efficiency of your research by significantly reducing exosome interference. For optimal performance, over 95% validated depletion and no prep required.
Cyclopamine is a Hedgehog (Hh) pathway antagonist with an IC50 of 46 nM in the Hh cell assay. Cyclopamine is also a selective Smo inhibitor.
SB431542 is a potent small molecule inhibitor of TGF-β signaling. Used for hESC neural differentiation and enhanced differentiation of PSCs into cardiomyocytes. Replaces SOX2 in reprogramming of fibroblasts into iPSCs.
CHIR99021 (GMP-grade) promotes self-renewal and pluripotency of embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). It can also maintain stem cells in an undifferentiated state and guide differentiation into specific lineages. Produced under GMP guidelines and is ideal for cell therapy research.
CHIR99021 potentiates self-renewal of human and mouse embryonic stem cells and enhances reprogramming of somatic cells into stem cells and also augments the differentiation potential of MSCs. Available as a lyophilized powder and in RUO or GMP-grade formats.
Captivate Bio's newly optimized CET Cocktail Kits are designed to enhance cell survival and promote growth of genetically stable hPSCs. Kits are configured to address specific workflows. Three versions include: CET Spark™ for 1L, CET Ignite™ for 5L, and CET Titan™ for 20L or more.
IWP 2 is a potent inhibitor of Wnt processing and secretion (IC50 = 27nM). IWP-2 has also been used in protocols to reprogram somatic cells to chemically-induced PSCs.
XAV939 is a potent tankyrase (TNKS) inhibitor. Promotes cardiomyocyte differentiation in mesoderm progenitor cells. Also used in neuronal differentiation protocols.
XAV939 (GMP-grade) is a potent tankyrase (TNKS) inhibitor. Promotes cardiomyocyte differentiation in mesoderm progenitor cells. Also used in neuronal differentiation protocols. Produced under GMP guidelines and is ideal for cell therapy research.
SU5402 is a potent and selective inhibitor of VEGFR-2, FGFR-1, and PDGFRB.