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An integrated stress response (ISR) inhibitor that promotes survival of pluripotent stem cells in culture when used in combination with Chroman 1 and Emricasan small molecules in the CEPT cocktail1.
Emricasan is an irreversible pan-caspase inhibitor. A key small molecule component of the published CEPT cocktail, enhances cell survival, clonogenicity, and cytoprotection of hPSCs.
PD0325901 is a selective, non-ATP-competitive inhibitor of the mitogen-activated protein kinase (MAPK/ERK kinase, or MEK) that suppresses expression of p-ERK1/2 and induces apoptosis. PD0325901 enhances generation of induced pluripotent stem cells (iPSCs).
The new NEST® 500 mL Conical Tube offers added capacity for your larger samples with a wide mouth design. This product is configured as follows: 500 mL and packaged in racks 4 per pack in a case of 24.
DBZ is an inhibitor of γ-secretase aspartyl protease that improves efficiency of iPSC generation and production of iPSCs from mouse and human keratinocytes without KLF4 and CMYC.
TPPB is a small molecule activator of protein kinase C, also known as α-amyloid precursor protein (APP) modulator or TBP.
CHIR99021 potentiates self-renewal of human and mouse embryonic stem cells and enhances reprogramming of somatic cells into stem cells and also augments the differentiation potential of MSCs. Available as a lyophilized powder and in RUO or GMP-grade formats.
L-Glutamine Solution (200 mM) is a ready-to-use stock solution. L-glutamine is an essential amino acid that is a required additive to most cell culture media, facilitating the storage and transfer of nitrogen to the cells in culture.
Captivate Bio offers a wide variety of NEST® cell culture inserts and multi-well plates. This product is configured as follows: 100mm dish with 1 cell culture inserts, 3.0 micron, PC Membrane, Translucent, TC-treated. Insert is packaged 1 per pack in a case of 10.
SB203580 is a selective ATP-competitive p38 MAPK inhibitor. Enhances the growth of mouse ES cells and enhances differentiation of cardiomyocytes from human ES cells.