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PD0325901 is a selective, non-ATP-competitive inhibitor of the mitogen-activated protein kinase (MAPK/ERK kinase, or MEK) that suppresses expression of p-ERK1/2 and induces apoptosis. PD0325901 enhances generation of induced pluripotent stem cells (iPSCs).
Emricasan is an irreversible pan-caspase inhibitor. A key small molecule component of the published CEPT cocktail, enhances cell survival, clonogenicity, and cytoprotection of hPSCs.
CHIR99021 potentiates self-renewal of human and mouse embryonic stem cells and enhances reprogramming of somatic cells into stem cells and also augments the differentiation potential of MSCs. Available as a lyophilized powder and in RUO or GMP-grade formats.
Z-VAD-FMK is a cell-permeable, irreversible pan-caspase inhibitor. Inhibits caspase processing and apoptosis induction in tumor cells.
SB203580 is a selective ATP-competitive p38 MAPK inhibitor. Enhances the growth of mouse ES cells and enhances differentiation of cardiomyocytes from human ES cells.
A83-01 has been extensively used in various studies to modulate TGF-β signaling pathways, impacting cellular differentiation, organoid growth, and disease modeling. A83-01 is supplied as a lyophilized powder.
SCF (Stem Cell Factor), Human, HEK293 is an essential factor in early hematopoiesis. Recombinant human protein expressed in human cell line for proper post-translational modifications and functionality.
TPO Protein, Mouse (CHO) is a hematopoietic factor that controls platelet production. This is a recombinant mouse protein expressed in mammalian CHO cells.
IL-2 is a cytokine primarily known for activating T cell proliferation and stimulates proliferation and differentiation of B cells, natural killer cells, monocytes, and macrophages. Recombinant IL-2 Protein, Human from Captivate Bio is available in various pack sizes.
IL-7 protein, human (HEK293, His) is an important hematopoietic cytokine that is essential for the development, expansion and survival of T cells and B cells.
