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Hedgehog pathway activator; Activates Smoothened (SMO). Purmorphamine has been shown to promote differentiation of motor neurons from human pluripotent stem cells and human and mouse mesenchymal stem cells.
Thiazovivin (GMP-grade) is a novel ROCK inhibitor that promotes hESC survival after single-cell dissociation. Improves the efficiency of fibroblast reprogramming and induction of iPSCs. This small molecule is produced under GMP guidelines making it ideal for cell therapy research.
Thiazovivin is a novel ROCK inhibitor with IC50 of 0.5 μM in a cell-free assay, promotes hESC survival after single-cell dissociation. Improves the efficiency of fibroblast reprogramming and induction of iPSCs.
Emricasan is an irreversible pan-caspase inhibitor. A key small molecule component of the published CEPT cocktail, enhances cell survival, clonogenicity, and cytoprotection of hPSCs.
