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StemRegenin 1 or SR1 is an antagonist of the aryl hydrocarbon receptor (AHR). SR1 promotes the expansion human hematopoietic stem cells and the generation of progenitor cells. This small molecule is available in custom pack sizes.
PD0325901 is a selective, non-ATP-competitive inhibitor of the mitogen-activated protein kinase (MAPK/ERK kinase, or MEK) that suppresses expression of p-ERK1/2 and induces apoptosis. PD0325901 enhances generation of induced pluripotent stem cells (iPSCs).
Captivate Bio's Soybean Trypsin Inhibitor (SBTI) is used in research primarily to inactivate trypsin during cell culture to stop the enzyme from degrading cells. This product is a powder format and available in various pack sizes including custom.
SANT-1 is a potent antagonist of Smoothened (Smo), which in turn inhibits Hedgehog (Hh) signaling, specifically targeting Shh-LIGHT2 (IC50 of 20nM) and SmoA1-LIGHT2 (IC50 of 30nM). SANT-1 aids in the generation of functional human pancreatic beta cells from human pluripotent stem cells (PSCs).
Interleukin-15 (IL-15) protein is a cytokine that regulates the immune system and is involved in the development of inflammation, cancer, and other diseases. IL-15 Protein, Human stimulates T cell, B cell, and NK cell activities.
Captivate Bio's DMEM/F12 basal medium is typically used as a classical basal formulation in low-serum and serum-free media formulations, when culturing hPSCs and 3D organoids. This formulation is with L-glutamine and Phenol Red.
A83-01 has been extensively used in various studies to modulate TGF-β signaling pathways, impacting cellular differentiation, organoid growth, and disease modeling. A83-01 is supplied as a lyophilized powder.
Captivate Bio's RPMI 1640 Medium is is suitable for a variety of mammalian cells. This classical formulation is modified with L-glutamine and Phenol Red.
L-685458 is a potent transition state analog (TSA) γ-secretase inhibitor (GSI). L-685458 is used in the research of neural research, Alzheimer’s disease, and various cancers.
Captivate Bio's Williams' E Medium, is a specialized basal media widely used for growing hepatocyte cells. This formulation has Phenol Red and no L-glutamine.
