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A83-01 has been extensively used in various studies to modulate TGF-β signaling pathways, impacting cellular differentiation, organoid growth, and disease modeling. A83-01 is supplied as a lyophilized powder.

LDN193189 dihydrochloride is a potent and selective ALK2 and ALK3 inhibitor. LDN193189 is a potent inhibitor of the bone morphogenetic (BMP) pathway, shown to contribute to the differentiation of pluripotent stem cells into functional pancreatic beta cells.