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PD0325901 (GMP-grade) is a potent, selective, and orally available inhibitor of MEK1/2, a protein crucial for the MAPK signaling pathway that regulates cell growth and proliferation. This small molecule is produced under cGMP and is ideal for cell therapy applications.
PD0325901 is a selective, non-ATP-competitive inhibitor of the mitogen-activated protein kinase (MAPK/ERK kinase, or MEK) that suppresses expression of p-ERK1/2 and induces apoptosis. PD0325901 enhances generation of induced pluripotent stem cells (iPSCs).
Modified MCDB 153 medium is specific for human epidermal keratinocyte culture, clonal growth of chicken embryo fibroblasts or Chinese Hamster Ovary (CHO) cells using low levels of Fetal Bovine Serum. This product is made-to-order by Sartorius and available in case packs only.
Captivate Bio's DMEM/F12 basal medium is typically used as a classical basal formulation in low-serum and serum-free media formulations, when culturing hPSCs and 3D organoids. This formulation is with L-glutamine and Phenol Red.
PLTMax® Human Platelet Lysate, clinical grade is for use in cGMP clinical applications and further certified to be endotoxin free. PLTMax is manufactured to meet the needs of research and development to ensure an easy transition to clinical manufacturing.
Captivate Bio's RESiVATE™ MSC Basal Medium is an optimized, baseline formulation that does not contain growth factors, cytokines, or unknown supplements, leaving you in full control of your experimental conditions.
CHIR99021 (GMP-grade) promotes self-renewal and pluripotency of embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). It can also maintain stem cells in an undifferentiated state and guide differentiation into specific lineages. Produced under GMP guidelines and is ideal for cell therapy research.
SB203580 is a selective ATP-competitive p38 MAPK inhibitor. Enhances the growth of mouse ES cells and enhances differentiation of cardiomyocytes from human ES cells.
As the very first HPL on the market, PLTMax® has been used as a manufacturing component in the generation of adult stems cells in clinical trials globally (Phase I to Phase III) in indications including neurology, gastrointestinal disease, wound repair and cardiology. Heparin required, US origin, research-grade, clinical-grade, and FDA Master File available.
Waymouth's Media is used for the establishment of carcinoma cell lines from pleural effusions and the growth of potentially tumorigenic cells. This product is manufactured by Sartorius and available in case packs only.