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PLTGold contains all the growth factors and proteins that maximize cell growth without the need to worry about animal-based additives or lot-to-lot variability. This product is a research-grade, xeno-free, heparin-free supplement. US origin.
Human Platelet Lysate (HPL) provides superior cell performance and cell expansion when compared to other supplements such as FBS or chemically defined media. PLTGold® HPL is a revolutionary xeno-free, heparin-free supplement which provides rapid cell expansion with proven success across various cell types including MSCs and immune cells (T cells and NK cells). Available in research and clinical grades, PLTGold® is an excellent supplement to cell culture media and for use in both 2D and 3D culture systems with a focus on research and cell therapy applications.
PLTGold® contains all the growth factors and proteins that maximize cell growth without the need to worry about animal-based additives or lot-to-lot variability. Other xeno-free hPLs compromise purity with particulates. With PLTGold® there is no clot formation and no need for heparin.
Cell Types: MSCs, T-Cells, NK Cells, Endothelial cells and more
Available in both clinical and research grades in 27mL, 100mL, 500mL, and 1000mL bottles.
Figure 2. Real time imaging of adipose-derived MSC growth using PLTMax® or PLTGold® Human Platelet Lysate as a media supplement showed increased cell growth kinetics compared to cells grown in medium supplemented with FBS or Human AB Serum.
Since Human Platelet Lysate is considered a biologic and not a drug, its submission and documentation are now handled by the FDA’s Center for Biologics Evaluation and Research (CBER), who recognizes these submissions with Master File numbers. CBER does not currently publish the Master Files on the FDA’s website.
Drug Master Files (DMF) are recognized by the FDA’s Center of Drug Evaluation and Research (CDER) agency for submissions made regarding the manufacturing, processing, packaging, and storing of human drug products. Master Files (MF) are recognized by the FDA’s Center of Biologic Evaluation and Research (CBER) agency for submissions made regarding the manufacturing, processing, packaging, and storing of human biologics. While there was overlap in regulatory oversight for biologics and drugs, the FDA created two independent specialized centers with premarket review and oversight responsibilities to deal with each product type, given their extremely different composition and manufacturing protocols
Large-scale expansion of cells including MSCs, T-cells, hematopoietic stem cells, iPSCs, tumor cells, and fibroblasts.
Both grades are manufactured under the same conditions and follow the same protocols. The clinical-grade product includes additional endotoxin testing and batch record documentation. All products have a CofA available.
Yes, with HPL it is possible to add too much to your cultures. We’ve seen that HPL can slow the growth of MSCs at high concentrations. Typically, we recommend using human platelet lysate at 2%-10% concentrations depending on your cell type.
Starting at $275.00
Starting at $55.00
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