DAPT

DAPT

SB203580

SB203580

Z-VAD-FMK

$350.00
In stock
SKU
SML18A
Description

Z-VAD-FMK is a cell-permeable pan-caspase inhibitor that irreversibly binds to the catalytic site of caspase proteases and can inhibit induction of apoptosis. Z-VAD-FMK has been shown to block TGF-beta1-induced apoptosis and inhibit CPP32-like protease activity in lysates in the pretreatment of hepatocytes.

Features
  • Broad-spectrum caspase inhibitor
  • Potent inhibitor of caspase-dependent inflammasomes
  • Blocks the induction of apoptosis
  • Each lot is highly pure (≥95%) and functionally tested
Specifications
Size5 mg
Molecular NameZ-VAD-FMK
Size10 mg
FormPowder
Alternative NamesZ-Val-Ala-Asp(OMe)-FMK; Z-VAD(OMe)-FMK;
Chemical NameL-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2- oxoethyl)-2-oxopropyl]-
Chemical FormulaC22H30FN3O7
Molecular Weight467.49
CAS Number187389-52-2
Purity≥98% by HPLC
Physical AppearanceWhite to off-white (Solid)
TargetCaspase
Shelf-Life3 years
ShippingRoom Temperature
StoragePowder: - 20°C for 3 years and 4°C for 2 years
Quality StatementThis product is for Research Use Only and is not intended for therapeutic or diagnostic use.
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