Triiodothyronine Salt Small Molecule

Triiodothyronine Salt

Repsox Small Molecule

RepSox

Retinoic Acid

$85.00
In stock
SKU
SML07F
Small Molecules for Stem Cell Research

Retinoic Acid (all-trans) is a metabolite of vitamin A that acts as a ligand for nuclear retinoic acid receptors (RARs, specifically RARα/β/γ) with an IC50 of 14nM and has a major effect on the differentiation and patterning of stem cells, and therefore in the development process (Rhinn & Dolle). In the process of differentiating mouse embryonic stem cells (ESCs), Retinoic Acid has been shown to promote the growth of glial cells and functional neurons in culture (Fraichard, et al.).

Furthermore, Retinoic Acid has played an important role in protocols involving the differentiation of human pluripotent stem cells (PSCs) into functional pancreatic β cells when combined with CHIR99021, SANT-1, Y27632, Compound E, RepSox, Triiodothyronine Salt, and other growth factors (Pagliuca, et al.).

Specifications
Molecular NameRetinoic Acid
Size500 mg
FormPowder
Alternative NamesRetinoic acid (AT), Retinoic acid (All-trans), All-trans retinoic acid (ATRA), NSC 122758, Trans retinoic acid, Tretinoin, Vitamin A acid, RA
Chemical Name(all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid
Chemical FormulaC20H28O2
Molecular Weight300.44
CAS Number302-79-4
PurityGreater than 95% by LCMS
Physical AppearanceLight yellow to yellow (Solid)
TargetRAR/RXR; PPAR; Endogenous Metabolite
Shelf-Life≥ 2 years (powder)
ShippingRoom Temperature
StorageStore at -20°C sealed, to protect from light and moisture
Quality StatementThis product is for Research Use Only and is not intended for therapeutic or diagnostic use.
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