PLTGold® Human Platelet Lysate, Pathogen-Inactivated, Clinical Grade

PLTGold® Human Platelet Lysate, Pathogen-Inactivated, Clinical Grade

PLTMax® Human Platelet Lysate

PLTMax® Human Platelet Lysate

PLTGold® Human Platelet Lysate

Rating:
97% of 100
Buy PLTGold today and save 10%, use promo code "PLTGOLD10" at checkout.
A growth factor rich, xeno-free, heparin-free supplement that is a superior alternative to FBS. Available in research and clinical grades.
As low as $350.00
In stock
SKU
HPL
Superior cell performance

Human Platelet Lysate (HPL) provides superior cell performance and cell expansion when compared to other supplements such as FBS or chemically defined media. PLTGold® HPL is a revolutionary xeno-free, heparin-free supplement which provides rapid cell expansion with proven success across various cell types including MSCs and immune cells. Available in research and clinical grades, PLTGold® is an excellent supplement to cell culture media and for use in both 2D and 3D culture systems with a focus on research and cell therapy applications.

Features
  • Heparin-free
  • Lot-to-lot consistency allowing for reproducible manufacturing
  • Rapid cell expansion when compared to FBS or chemically-defined media
  • Sourced from FDA-registered blood centers
  • FDA Drug Master File available



Sample Data

Figure 2. Real time imaging of adipose-derived MSC growth using PLTMax® or PLTGold® Human Platelet Lysate as a media supplement showed increased cell growth kinetics compared to cells grown in medium supplemented with FBS or Human AB Serum.

Specifications
Intended useMedia supplement, cell culture, cell therapy research, drug discovery, MSCs, T Cells, Hematopoietic Stem Cells, and iPSCs
Osmolality250 - 330 mOsm/kg
Endotoxin< 10.0 EU/mL (available on clinical grade only)
Shelf-Life36 months from date of manufacture
pH6.8 - 7.8
Storage- 20 °C
MycoplasmaNot Detected
Cellular KineticsPass
Platelet TestingInfectious diseases including HIV-1, HIV-2, HIV-NAT, HCV, HBsAg, and serologic tests for Syphilis, ZIKV NAT, WNV NAT
Total Protein4.0 - 6.5 g/dL
SourceUS donors, AABB-accredited and FDA-registered blood banks
How much human platelet lysate should I add to my media or cultures?

Cells grown in human platelet lysate typically use half the concentration compared to cells cultured in fetal bovine serum. Standard protocols suggest adding 5% concentration. However, we recommend titrating anywhere between 2-10% in order to maximize cell growth and narrow in on the best concentration for your cultures.

Is it possible to add too much HPL to my cultures?

Yes, with HPL it is possible to add too much to your cultures. We’ve seen that HPL can slow the growth of MSCs at high concentrations.

What is the difference between research-grade and clinical-grade human platelet lysate?

Both grades are manufactured under the same conditions and follow the same protocols. The clinical-grade product includes additional endotoxin testing and batch record documentation. All products have a CofA available.

What is PLTGold human platelet lysate?

PLTGold is a completely xeno-free human platelet lysate which contains all essential growth factors for healthy cell growth. Donor units are pooled in large batches and manufactured by Mill Creek Life Sciences under a proprietary method to produce highly consistent and reliable lots.

Can PLTGold be used in clinical trials?

Yes, PLTGold is a completely xeno-free supplement that does not require heparin (or used in the manufacturing process). PLTGold has an FDA registered drug master file available for reference.

What is the intended use for platelet lysate?

Large-scale expansion of cells including MSCs, T-cells, hematopoietic stem cells, iPSCs, tumor cells, and fibroblasts.

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Superior Alternative

Superior xeno-free alternative to FBS and serum-free media solutions. Minimizes lot-to-lot variability.

Rapid Cell Growth

Contains growth factors that maximize cell growth without the need to worry about animal-based supplements.

Full Donor Screening

Certificates of Analysis, Certificate of Origin and Compliance available.

FDA DMF Available

HPL has been used to grow cells in various clinical trials around the world.